Inflammatory CNS Diseases

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Category: Neurology Club
Published on: 25.02.2015

Presenter:

Dr Laurent Garosi DVM Dip ECVN MRCVS
RCVS & European Specialist in Veterinary Neurology
Head of Neurology/Neurosurgery- Davies Veterinary Specialists

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About The Webinar

Meningoencephalomyelitis of unknown etiology (MUE) in the dog comprises a variety of conditions that are thought to be immune mediated in nature and which involve inflammation of the brain, meninges, and/or spinal cord. MUE is the umbrella term used to encompass granulomatous meningoencephalomyelitis (GME), necrotising leukoencephalitis (NLE) and necrotising meningoencephalitis (NME). Granulomatous meningoencephalomyelitis (GME) is an angiocentric, mixed lymphoid, infiltrative process that predominantly affects the CNS white matter and leptomeninges. The clinical signs of all these conditions vary depending on those parts of the nervous system where the lesions are most severe. Commonly, however, the clinical picture is one of multifocal, asymmetric, intracranial disease seen in a young to middle aged (or older) small breed dog.

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